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Methotrexate
Methotrexate is an antimetabolite used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. This medicine works by interfering with cell growth and by suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function. This medicine may also be used to treat other conditions as determined by your doctor, including lupus and psoriatic arthritis.
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Methotrexate 2.5mg (Generic) |
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| Name: Methotrexate 2.5mg (Generic) |
Strength: 2.5mg |
Form: Pill |
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| Qty | 240 | |
120 | |
90 | |
60 | |
30 | |
| Price | $180.00 | |
$105.00 | |
$78.00 | |
$52.00 | |
$30.00 | |
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| Product Information |
Directions on how to take
Follow the directions for using this medicine exactly as provided by your doctor. This is a potent medicine. The dose and how often you take it is based on your medical condition and response to therapy. There are many different dosing schedules for this medicine (especially for cancer treatment). Therefore, it is very important that you follow your doctor's instructions carefully. Do not exceed the recommended dose or take this medicine for longer than prescribed without checking with your doctor. Your condition will not improve any faster and the risk of serious side effects may be increased. For managing psoriasis or rheumatoid arthritis, take this medicine exactly as directed, usually once a week. Drinking extra fluids while you are taking this medicine is recommended. This helps your kidneys to remove the drug from your body and minimize some of the side effects. If nausea, vomiting, or loss of appetite occur, ask your doctor, nurse, or pharmacist for ways to lessen these effects.
Warnings and Precautions
It may take several months of continued use for the full benefit of this medicine to be seen in the management of psoriasis or rheumatoid arthritis. Do not stop using this medicine without checking with your doctor. Certain antibiotics (e.g., chloramphenicol, sulfa, tetracyclines) may interfere with methotrexate blood tests (increase methotrexate blood levels due to protein-binding displacement). Make sure laboratory personnel and your doctors know you are using any of these types of antibiotics. This medicine may cause dizziness or drowsiness. Do not drink alcohol while you are taking this medicine. This medicine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. This medicine may reduce the number of blood cells which are needed for clotting. To prevent bleeding use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised or injured. This medicine may lower your resistance to infection. Do not have immunizations/vaccinations without the consent of your doctor and avoid contact with people who have recently received oral polio vaccine. Certain side effects, such as mouth sores, may be reduced by taking a folic acid supplement. Talk with your doctor or pharmacist about the use of folic acid supplements to determine if one is right for you.
Possible side effects
Side effects may include nausea, vomiting, stomach pain, drowsiness or dizziness, mouth sores, diarrhea, fever, fatigue, persistent sore throat, unusual bleeding or bruising, black stools, skin rash, enlarged glands/lymph nodes, dark urine, bone pain, or unusual pain and discoloration of the skin, yellowing of the eyes/skin, change in the amount of urine, chest pain, dry cough, trouble breathing, calf pain/swelling, vision changes, irregular heartbeat, muscle weakness, mental changes, or seizures. Temporary hair loss may occur. Normal hair growth should return after treatment has ended. Symptoms of an allergic reaction may include rash, itching, swelling, severe dizziness, or trouble breathing. If symptoms persist, consult your doctor.
Storage
Store this medicine at room temperature between 59 and 86 degrees f (15-30 degrees c) in a tightly-closed container, away from light, and moisture.
Additional information
Rarely, methotrexate has caused serious (possibly fatal) side effects. This medicine should be used only to treat cancer or severe cases of psoriasis or rheumatoid arthritis. Methotrexate has caused birth defects and fetal death. Women must avoid becoming pregnant while taking this medicine. Pregnant women who have psoriasis or rheumatoid arthritis must not use methotrexate. (see cautions) if you have kidney problems/excess body water (ascites, pleural effusion), you must be monitored and your dose may be adjusted or stopped by your doctor. Infrequently, methotrexate (usually at high dosages) has caused severe (possibly fatal) bone marrow suppression (decreasing your body's ability to fight infection) and stomach/intestinal disease (e.g., bleeding) when used with nonsteroidal anti-inflammatory medicines (nsaids) (e.g., ibuprofen, naproxen). This medicine may rarely cause liver problems when used for long periods of time. If you are using methotrexate long-term, liver biopsies should be performed. Rarely, methotrexate use has resulted in serious (possibly fatal) lung problems/infections (pneumocystis carinii pneumonia), skin reactions, diarrhea and mouth sores (ulcerative stomatitis). (see side effects) very rarely, lumps (tumors/abnormal growths) may appear during methotrexate use. The drug must be stopped and treatment may be needed. Consult your doctor immediately if new lumps/growths occur. When used to treat tumors, methotrexate may cause side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). Tell your doctor immediately if you experience symptoms such as irregular heartbeat or muscle weakness. Although rare, this medicine when used with radiation therapy may increase the risk of tissue/bone damage. Discuss the risks/benefits of your treatment with your doctor.
Disclaimer
The drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Alergy Relief
